Stroke Oxygen Study

A multi-centre, prospective, randomised, open, blinded-endpoint study to assess whether routine oxygen treatment in the first 72 hours after a stroke improves long-term outcome

The Stroke Oxygen Study is now complete and the results have been published (see below). Many thanks to the patients who participated, the stroke survivors who helped with the design and running of the study, the collaborating centres, and the SO2S team.

Results of the SO2S Main study

 Effect of Routine Low-Dose Oxygen Supplementation on Death and Disability in Adults With Acute Stroke: The Stroke Oxygen Study Randomized Clinical Trial. JAMA 2017;318:1125-1135.

Routine low-dose continuous or nocturnal oxygen for people with acute stroke: three-arm Stroke Oxygen Supplementation RCT. Health Technol Assess 2018;22(14).

 SO2S Protocol (click here)

SO2S Statistical Analysis Plan (click here)

Patient and Carer Focus group  (click here)

 SOS Pilot study (week 1 results) (click here)

SOS Pilot study (6 month results) (click here)


Click here for BUCS SO2S portal  

Professor Christine Roffe
Stroke Research in Stoke
Guy Hilton Research Centre
1 Thornburrow Drive
Stoke-on-Trent ST4 7QB
Email mail@so2s.co.uk